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diagnosis rheumatology differential erythematosus vasculitis ana antinuclear classification management table antibodies aortitis arthritis autoantibodies criteria cryoglobulinemia cryoglobulins disease druginduced laboratory
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... , oral ulcers, Lupus ... #lupus #Systemic ... Management #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... (SLE), Sjogren's ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... bullous or vesicular eruption ... and branches • GCA ... lupus erythematosus ... vasculitis, and SLE
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... is clinically suspected ... autoantibodies #Systemic ... #diagnosis #rheumatology ... #table #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... macular, patchy eruption ... Diagnosis: • ANCA-associated ... #Systemic #Lupus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... Clinical and Immunologic ... Criteria CLINICAL ... #SLE #Lupus #Erythematosus
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Cell Arteritis (GCA ... Nodosa (PAN), ANCA ... Arthritis (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Elevated ESR and CRP GCA ... develop in pts with GCA ... bullous or vesicular eruption ... Differential #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... (SLE), rheumatoid
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