20 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
(CNS) involvement ... Inflammatory causes ... • Sjögren syndrome ... erythematosus ... optica spectrum disorder
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... & renal involvement ... heart block • Sjogren ... #Lupus #Erythematosus ... #rheumatology #management
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS ... Comorbid autoimmune disorders ... (Systemic lupus ... erythematosus, ... Sjögren syndrome
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... autoimmune (RA, Sjogren's ... Lupus Erythematosus ... (total 50, renal
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren ... ) • Endocrine disorders ... and CNS • Headache ... APLA/LAC: • Renal
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... drug-induced SLE) • Systemic ... • Sjögren syndrome ... polyangiitis without renal
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
toxoplasmosis Autoimmune disorders ... syndrome, Still ... disease, systemic ... lupus erythematosus ... sarcoidosis Iatrogenic causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... #Diagnosis #Management
Causes of Acute Pericarditis:

Infectious;

Viral: 
Adenovirus 
Coxsackie virus A and B 
Echovirus 
Epstein-Barr virus 
Hepatitis 
Human immunodeficiency
Causes of Acute ... Procainamide Metabolic disorders ... : Renal Insufficiency ... syndrome Systemic ... lupus erythematosus