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systemic vasculitis antibodies antinuclear classification antibody antineutrophil aortitis bee cerebritis champs complement cryoglobulins dermatology diseases hypocomplementemia inflammatory low mnemonic nonpalpable
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... erythematosus ... • Sjögren syndrome ... Jcortesizaguirr #ANA ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
SLE), Sjogren's ... : Lupus (SLE), Systemic ... Lymphoproliferative Disorders ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... #SLE #Summary #diagnosis ... #rheumatology # ... management
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... Inflammatory causes ... • Sjögren syndrome ... erythematosus ... • ANCA-associated
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... antibodies • (-) ANA ... #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Erythematosus ( ... total 50, renal ... #differential # ... hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... (e.g. systemic lupus ... erythematosus ( ... syndrome) #Cryoglobulinemia ... classification #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Nodosa (PAN), ANCA ... (RA), Systemic lupus ... erythematosus ( ... SLE), Sarcoidosis ... #Diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vasculitis/HSP • Cryoglobulinemia ... (MIXED) • ANCA ... , Sjogren's ... #Diagnosis #hematology ... #rheumatology #
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