11 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... implications : TTP ... #purpura #TTP # ... #Comparison #Diagnosis ... #Table #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... , Hematology 2012
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... • Thrombotic Thrombocytopenic ... Purpura (TTP) ... Microangiopathy #TMA #hematology ... differential #diagnosis #HUS
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Pregnancy - TTP ... /HUS, HELLP Syndrome ... plasma exchange 2) TTP ... #obstetrics #hematology ... #comparison
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) ... Diagnosis of TTP ... • Distinguish TTP ... #treatment #rheumatology ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: ITP • Secondary ... disease - DIC/TTP ... Defects: • DIC, TTP ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
of child 3) TTP ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... DDX: • TMA’s (HUS ... /TTP/DITMA) - ... Schistocytes - MAHA: TTP ... treatment #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... differential #diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... (PTP): Occurs 7 ... Causes purpura & ... severe thrombocytopenia ... diagnosis #management #hematology