112 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE ... #hematology #rheumatology ... differential #diagnosis #causes
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... Dermatomyositis Erythema ... Lyme disease Erythema ... IBD • RA • SLE ... differential #diagnosis #rheumatology
Erythema Annulare Centrifugum (EAC),
This is erythema annulare centrifugum (EAC), one of the “figurate erythemas.” These lesions
Erythema Annulare ... EAC), This is erythema ... the “figurate erythemas ... Most cases are idiopathic ... EAC #clinical #photo
Erythema Nodosum: In this case, E. Nodosum has occured secondary to 
Streptococcal infection.
Photo credit, Josh Fierer,
Erythema Nodosum ... : In this case, ... Photo credit, Josh ... Dermatology #SkinRash #Erythema ... #ENodosum #Photo
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Associated - SLE ... reactions • Erythema ... Differential #Diagnosis #hematology ... #rheumatology #
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... • Special cases ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... Usual therapeutic management ... Erythematosus #Diagnosis #Management ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... Discontinuation of causal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... Diagnosis #Algorithm #Causes ... #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE ... Summary #diagnosis #rheumatology ... #management