12 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphadenopathy ... Lupus Erythematosus ... #Causes #Hematology ... #Oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematosus) ... (ACLE) • Erythematous ... rashErythematous ... #Erythematosus
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Auto-Antibodies ... #Erythematosus ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... #diagnosis #differential
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Diagnosis Algorithm ... inflammation is secondary ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
lymphogranuloma venereum, primary ... and secondary syphilis ... Still disease, systemic ... lupus erythematosus ... sarcoidosis Iatrogenic causes
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... #clues #system ... #erythematosus # ... rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... lupus erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... [SLE], AOSD) •
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Pain (Otalgia) - Differential ... Relapsing, bilateral, erythematous ... of Secondary Otalgia ... • Lymph node: lymphadenopathy ... Otalgia #Ear #Pain #Otology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... ischemia - Skin: erythematous ... mucositis - Rash ... lupus erythematosus ... vasculitis, and SLE