21 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... cause ischemia and ... (@neudrawlogy) and ... #SLE #CNS #neurology ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... rashErythematous ... alopecia Differential ... and CNS • Headache ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... #signs #symptoms ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
with PTU (50%) and ... weeks to months) and ... of autoantibodies ... Systemic Lupus Erythematosus ... comparison #table #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Clinical Domains ... least 2 joints • Neurologic ... low C4, Low C3 and ... #Criteria #SLE ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA) is common and ... Rarely dominate the clinical ... joints • Oral and ... Polyangiitis #GPA #dermatology ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... and physical exam ... likely it will be clinically ... #patterns #rheumatology ... #diagnosis #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... untreated, Behave and ... response to treatment and ... #pathophysiology ... #Hematology #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Amyloidosis and ... histiocytosis, and ... Scleromyxedema (CNS ... @KirtanPatolia and ... Paraproteinemias #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and ... Diagnosis and Workup ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... Causes #Workup #hematology