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diagnosis rheumatology lupus sle erythematosus hematology syndrome vasculitis comparison hand oncology photo table treatment activation adultonset algorithm als amyotrophic antinxp2
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... Classification: ... permanent alopecia Differential ... lymphoproliferative syndrome Clinical
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Evolution: Chronic disease ... #Erythematosus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... • Ulcerated, erythematous ... reticularis Differential ... #rash #diagnosis
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
painless nodular rash ... Papulonodular, erythematous ... , painless, no systemic ... biopsy preferred Differential ... University Infectious Diseases
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... fraction < 20% Differential ... solid cancers • Systemic ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... (SLE) Clinical ... Cerebrovascular Disease ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... ischemia - Skin: erythematous ... mucositis - Rash ... lupus erythematosus ... #rheumatology #classification
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Ig deposition disease ... #Diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Fever is the main clinical ... Petechial or purpuric rash ... lupus erythematosus ... Syndrome #Diagnosis #Management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... extensive skin rash ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology ... #diagnosis #management
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