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Polycythemia (Erythrocytosis) - Pathophysiology

#Polycythemia #Erythrocytosis #Pathophysiology #hematology #algorithm #differential #diagnosis
Polycythemia (Erythrocytosis ... Pathophysiology #Polycythemia ... #Erythrocytosis
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... (Erythrocytosis ... Increased PMNs • Polycythemia ... #Erythrocytosis ... Diagnosis #Algorithm #Causes
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Erythrocytosis - ... Polycythemia Differential ... - Acquired Causes ... MatthewHoMD #Erythrocytosis ... #Polycythemia #
Clues to Differential Diagnosis of Central Cyanosis: Onset of cyanosis, Clubbing, Secondary erythrocytosis, Auscultation, X-ray, Echocardiography,
Clues to Differential ... Clubbing, Secondary erythrocytosis ... Central #Cardiology #Causes
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Instead, pause, ... Most polycythemia ... about secondary causes
Differentiating Features Between Central and Peripheral Cyanosis

Mechanism - Arterial destauration
Sites - Skin, mucous membrane of oral
Present Secondary erythrocytosis ... therapy - Pulmonary cause ... Absent Secondary erythrocytosis
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocythemia • Polycythemia ... Differential #Diagnosis #causes
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... disorders (eg. polycythemia ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... myelogenous leukemia • Polycythemia ... Diagnosis #Algorithm #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... thrombocytosis • Polycythemia ... Diagnosis #Algorithm #Causes