11 results
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Estimating the Total ... Dose (TDD) of Insulin ... #dosing #estimation ... #pharmacology #endocrinology ... #diabetes #DM2
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... deficit: - Type I DM ... - Type II DM ... #dka #hhs #pathophysiology ... #comparison #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications Summary ... Table Insulin ... comparison #management #endocrinology ... #dm2
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... cells, triggering insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... • Increases insulin-mediated ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
The “twin cycles” of diabetes, first introduced by Roy Taylor in 2008.  
#fatty liver #fatty
diabetes #t2d #dm2 ... #insulin resistance ... #pathophysiology ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology Summary ... glucose-dependent insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management Summary ... • Metabolic: Insulin ... Acromegaloid): insulin ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Unknown cause Treatment ... Etoposide/VP16 (100 mg/m2 ... diagnosis #management #treatment ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management Summary ... pneumonia • DM ... Lung Abscess Pathophysiology ... hemorrhage • Treatment ... several months of treatment