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diagnosis management differential algorithm erythematosus hematology infectiousdiseases lupus oncology summary systemic apml cancer cerebritis chf cirrhosis clinical cns criticalcare differentiation
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... CNS #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Unknown cause Treatment ... inhibitors under evaluation ... #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... Renal Failure Treatment
Causes of ST Segment Elevation - Differential Diagnosis Framework STEMI: • Upsloping convex STE: "Pardee's sign" +
interval J Wave Syndromes ... involved • Brugada Syndrome ... QRS complex Pulmonary ... Wolff-Parkinson-White syndrome ... differential #diagnosis #cardiology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
to be in ADHF starts ... with presence of pulmonary ... acute coronary syndrome ... algorithm #management #cardiology ... #treatment #table
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
host): • Chronic pulmonary ... symptoms • Rheumatologic ... Histoplasmosis Treatment ... Inhalation of spores ... Aspergillosis Pathophysiology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
vancomycin (if SSTI or port ... interventional radiology ... → no immediate treatment ... after CRS) - Treatment ... renal failure, pulmonary
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... #Rheumatology #
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
Hepatopulmonary Syndrome ... abnormalities PATHOPHYSIOLOGY ... the left heart TREATMENT ... only definitive treatment ... improvement or resolution
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