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Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
/9780323449427/critical-care-nephrology ... Action #Location #Nephrology ... #Pathophysiology ... #Pharmacology
Systemic Glucocorticoid Dose Equivalents. 

Note: approximate equivalent dose is based on anti-inflammatory potency. Fludrocortisone is not
mineralocorticoid activity ... anti-inflammatory activity ... (postoperative nausea ... Steroid #Conversion #Table ... #Equivalents #Pharmacology
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... differential #diagnosis #pathophysiology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Secondary Causes ... based on repeat clinic ... Steroids (Cushing's, exogenous ... RAS Metabolic Causes ... HTN #Secondary #Nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Action, Effects, Clinical ... #Medications #Pharmacology ... #summary #table ... #nephrology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
organic acids and bases ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively ... #nephrology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
an identifiable cause ... The cause is unknown ... but its clinically ... #Bells #Palsy #neurology ... #anatomy #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
of dopaminergic activity ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
For my UME micro course, I made a figure that captures this terminology and lets learners
the spectrum of clinically ... important drug classes ... does not equal clinical ... #antibiogram #pharmacology ... management #spectrum #table