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diagnosis management erythematosus hematology systemic ana antinuclear antiphospholipid apls autoantibodies cerebritis classification cns cryoglobulinemia cryoglobulins hemeonc hemophagocytic hlh hypercoagulable lymphohistiocytosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease activity ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis #rheumatology ... #table #ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • They can cause ... : • Clinical triad ... (e.g. systemic lupus ... classification #rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... symptoms are not caused ... skin (16-32%): lupus
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup Algorithm ... - 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... Clinical Presentation ... Pathophysiology ... absent NK-cell activity ... Diagnosis #Management #Hematology
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