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diagnosis management differential nephrology erythematosus hematology signs symptoms systemic treatment algorithm barre guillain sle workup agraphia alexia alkalosis allergy als
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #rheumatology #
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
based on repeat clinic ... • Nephritic syndrome ... Excess: • Conn's syndrome ... Steroids (Cushing's, exogenous ... HTN #Secondary #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively ... #nephrology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... Clinical Features ... extremity edema, active ... Erythematosus #Diagnosis #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease activity ... Farr assay) and lupus ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • They can cause ... : • Clinical triad ... (e.g. systemic lupus ... classification #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... involvement: Intractable nausea ... Other brainstem syndromes ... disorders (Systemic lupus ... Manifestations #diagnosis #neurology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... production • Actively ... maintained fever CAUSES ... Phaeochromocytoma Neurologic ... #Differential #Causes
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... of dopaminergic activity ... , asthenia • Neurologic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... skin (16-32%): lupus ... • Heerfordt syndrome
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