14 results
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli ... #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... glomerulonephritis #nephrotic ... #nephritic #nephrology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Secondary Causes ... based on repeat clinic ... Glomerulonephritis • Nephritic ... Steroids (Cushing's, exogenous ... HTN #Secondary #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Mesangiocapillary GN • Active ... dysmorphic RBC, RBC casts ... formation along glomerular ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
Summary CLINICAL ... • Nephritic syndrome ... (Casts) • Marked ... proteinuria (may be nephrotic ... GlomeruloNephritis #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... initial #testing #nephrology ... #nephrotic #nephritis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia: • Nephrotic ... #diagnosis #management
Indications for tPA in Stroke:
 • Clinical diagnosis of ischemic stroke
 • Measurable neurologic deficit
 •
in Stroke: • Clinical ... present, in which case ... hemorrhage • Active ... #Stroke #cva #management ... #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... - Causes progressive ... by decreasing activity ... Lateral #Sclerosis #neurology ... #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... Clinical Manifestations ... SPS #Diagnosis #Management ... #treatment #neurology