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management rheumatology signs sle syndrome hematology differential erythematosus oncology classification clinical manifestations photo activation acute algorithm allergy anaphylaxis autoantibodies canimorsus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... - Hemolytic anemia ... Lupusreference #SLE #Systemic ... #signs #symptoms
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash #dermatology ... #Algorithm #causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Malar (butterfly) Rash ... decr release and activity ... pathophysiology #diagnosis ... #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... months to years) Systemic ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... The signs and symptoms ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
air conditioning system ... Bandemia, AKI. ... dogs & latter can cause ... the key to the diagnosis ... #dermatology #clinical
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