42 results
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... conjunctivitis, cough, rash ... #coronavirus #diagnosis ... #Signs #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... hair follicles -> causes ... decr release and activity ... pathophysiology #diagnosis ... #signs #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... can present with rash ... , Shaw sign, holster ... anti-synthetase syndrome ... Can also see mechanics
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
- Differential Diagnosis ... sclerosis (white "ash ... McCune Albright syndrome ... disorders #skin #dermatology ... #Algorithm #causes
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused ... arthritis • SLE
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... psoriasis (7-30%) • Inflammatory ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... Differential Diagnosis ... extremity edema, active ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... The signs and symptoms ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Guillain-Barré syndrome ... erythematosus (SLE ... Atorvastatin Diagnosis ... increased spontaneous activity ... toxicity #myopathy #diagnosis