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Hepatorenal Syndrome - Diagnosis and Management Summary Who gets HRS? • Decompensated cirrhosis • Typically with existing
Summary Who gets HRS ... of treatment in HRS-AKI ... • Splanchnic/extrarenal ... Octreotide 50mcg/hr ... Hepatorenal #Syndrome #HRS
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Framework PRERENAL: - Intrarenal ... urinary outflow - Extrarenal ... retroperitoneal fibrosis - Intrarenal
Diagnosis of Hypokalemia - Differential Algorithm Categorized by Causes: Redistribution, Extrarenal Losses, Renal Losses (High and
Redistribution, Extrarenal
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
bicarbonate - Extrarenal ... Hypomagnesemia - Extrarenal
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
mOsm/kg - Implies extrarenal ... Volume Status Extrarenal
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome (HRS ... Diagnostic Criteria HRS-AKI ... previously known as HRS ... Type 2) • HRS-AKD ... @drkeithsiau #HRS
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status Hypervolemic hypernatremia - CHF
nephropathy Extrarenal
Pathophysiology of Hepatorenal Syndrome - Dilation of splanchnic arteries initially compensated by increased CO eventually decompensates
failure due to intrarenal ... Hepatorenal #Syndrome #HRS
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
access to water Extrarenal
Hypokalemia Differential Diagnosis Algorithm Low intake • poor oral intake Renal loss • Medication • Hypomagnesemia •
Bartter's syndrome Extrarenal
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