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Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... Framework PRERENAL: - Intrarenal ... urinary outflow - Extrarenal ... retroperitoneal fibrosis - Intrarenal ... Acute #Kidney #Injury
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
causing Acute Kidney Injury ... Diuretics • Altered intrarenal ... cyclosporine, tacrolimus) Intrarenal ... Acute #Kidney #Injury
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... below level of injury ... spinal artery injury ... below level of injury
Diagnosis of Hypokalemia - Differential Algorithm Categorized by Causes: Redistribution, Extrarenal Losses, Renal Losses (High and
Redistribution, Extrarenal
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... hepatorenal syndrome) Intrarenal ... Acute #Kidney #Injury
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
mOsm/kg - Implies extrarenal ... Volume Status Extrarenal
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
bicarbonate - Extrarenal ... Hypomagnesemia - Extrarenal
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status Hypervolemic hypernatremia - CHF
nephropathy Extrarenal
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
access to water Extrarenal
Hypokalemia Differential Diagnosis Algorithm Low intake • poor oral intake Renal loss • Medication • Hypomagnesemia •
Bartter's syndrome Extrarenal
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