37 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... Guillain-Barré syndrome ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome ... Treatment:
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebritis: Labs, Imaging ... Puncture, EEG Treatment ... Secondary prevention (statin ... diagnosis #management #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome ... Imaging - CT Chest
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Abdominal compartment syndrome ... Losses, Third Spacing ... Dehydration Shock Treatment ... criticalcare #algorithm #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Drugs (Statins), ... oxidative iniury Treatment ... Summary #causes #treatment
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
after Congo red staining ... diagnosis and treatment ... AL #lightchain #NEJM
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... within 7 days of starting ... spontaneously (before any treatments ... malignancies Treatments ... #Tumor #Lysis #Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Imaging Patterns ... Testing: • Imaging ... epilepticus Treatment ... underlying cause • Treatment
PCOS Treatment
1st line = weight loss
 • 5-10% weight loss can restore ovulatory cycles
 • Improvement
PCOS Treatment ... Electrolysis, shaving ... waxing #PCOS #Treatment ... Polycystic #ovary #syndrome
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... coagulopathy common • Imaging ... Renal Failure Treatment ... Differentiation #Syndrome