20 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... and diplopia) • Vascular ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... intrapulmonary vascular ... shunt (Type 2) Clinical ... 10 minutes of rest ... Intra-pulmonary vascular
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the clinical ... /or suspicious clinical ... presence of metabolic syndrome ... body mass index; FBC ... Liver #Enzymes #Differential
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Summary Clinical ... Budd Chiari syndrome ... (involvement IVC ... initial test: abdominal
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... abnormalities • Muscular ... Pulmonary: pleural effusion ... Disease #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
anti-GBM) Other tests ... o infection • Echocardiogram ... LVEF, pericardial effusion ... #differential # ... diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... HoTN, edema and effusions ... initiation • Differential ... APML #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Bedside: ice pack test ... /Edrophonium test ... Gravis #diagnosis #management
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... Frontal atrophy Vascular ... MNCD #Dementia #Differential
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... : • Nephrotic syndrome ... activity of factor X, vascular ... Persistent pleural effusions ... Testing: • EKG • Echocardiogram