22 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Congenital intrinsic coagulation ... intravascular coagulation ... Jcortesizaguirr #Abnormal ... differential #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... , FVII, FIX, FX ... amyloidosis #Abnormal ... differential #hematology #coagulation
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... Tests - Prolonged PT ... and Prolonged PT ... #Coagulation #Abnormal
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
(INR), Normal PTT ... Prolonged PTT, Normal ... Prolonged PTT, Normal ... Differential #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... than bleeding) ABNORMAL ... PT/NORMAL PTT: ... PT/ABNORMAL PTT
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Expected: Low (or normal ... factors, Can be normal ... using INR use PT ... Expected: Low (or normal ... clots, Can be normal
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... levels of factors VII ... Fibrinogen: ↓ • PT ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
Normal Thromboelastogram ... Diagnosis #Hematology #Coagulation ... #Thromboelastogram ... #TEG #Normal #Interpretation
Paracentesis Anatomy Landmarks

Don't hit the inferior epigastric artery!!! Go 2cm below the umbilicus in the midline
spine Overall coagulation ... is usually NORMAL ... cirrhosis, despite abnormal ... tests of coagulation ... Prolonged PT) because
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Differential Diagnosis Algorithm ... Destruction • Abnormal ... • Vasculitis Coagulation ... deficiencies Coagulation ... Differential #Diagnosis #Algorithm