3398 results
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Initiation phase caused ... by tissue factor's ... intrinsic X-ase; factors ... cross-linked by Factor ... models #hematology #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Acquired Risk Factors ... Thrombophilia: - Factor ... cardiovascular risk factors ... coagulation and other causes ... Venous #Arterial #pathophysiology
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... most possible causes ... bind to intrinsic factor ... #Differential #Causes ... #Diagnosis #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAIDs cause vasoconstriction ... use shouldn't cause ... additional risk factors ... Nephrology #Renal #Pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
patientsl • Risk factors ... blood donor • Pathophysiology ... without other cause ... patients • Risk factors ... transfusion • Pathophysiology
Causes of Atrial Fibrillation

Heart disease 
 - Aging heart 
 - Cardiomyopathies 
 - Congestive heart
Causes of Atrial ... Extracardiac factors ... AFib #Cardiology #Pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... Risk Factors: ... are the leading cause ... Differential #Diagnosis #Pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Caused commonly ... Pathophysiology: ... Risk factors: age
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
environmental factors ... Lack of B12 as a cofactor ... Manic #Secondary #Causes ... Differential #Diagnosis #Pathophysiology