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diagnosis hematology differential pt prolonged aptt bleeding bruising cascade management anticoagulant anticoagulation apixaban arterial clot cryofibrinogenemia dabigatran dic disorders disseminated
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... Initiation phase caused ... , resulting in coagulation ... EricsMedicalLectures/ #Coagulation ... #hematology #pathophysiology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Jcortesizaguirr #Abnormal ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... amyloidosis #Abnormal ... #differential #hematology ... #coagulation
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... Prolonged PTT, Normal ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... factor == NORMAL ... intravascular coagulation ... discern these causes ... Differential #Diagnosis #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... Complete blood count coagulation ... #Causes #dermatology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... generated by Tissue Factor ... #Coagulation #Cascade ... PTT #diagnosis #models ... #hematology #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Acquired Risk Factors ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
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