177 results
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
Factor Activity ... Type of Factor ... ) Units of Factor ... #hemophilia #hematology ... #factorix
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... #Diagnosis #Hematology ... CHADS2VASc #HASBLED #Comparison
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Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... Treatment - Acute Bleeding ... serious or moderate bleeding ... Avoid meds that ↑ bleeding ... Management #treatment #hematology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Thrombosis and Bleeding ... von Willebrand factor ... #Thrombosis #Bleeding ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... with very high bleeding ... based on high bleeding ... Anticoagulation #Factors ... #Hematology #Diagnosis
Evaluation Algorithm of Patients with Bleeding

#Differential #Bleeding #Superficial #Deep #Causes #Algorithm #Hematology
Patients with Bleeding ... #Differential #Bleeding ... Causes #Algorithm #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... protein C and S Pathophysiology ... Exposure → Tissue factor ... treatment #management #hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... first variceal bleeding ... Prevention of variceal rebleeding ... BetaBlockers #Cirrhosis #hepatology