329 results
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor ... #Hemostasis #Pathophysiology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... could be multiple factors ... Decreased factor ... Factor consumption ... Causes #diagnosis #differential
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Patient has a factor ... Patient has a factor ... diagnosis #hematology #pathophysiology
On the INR of FFP - why transfusing for INR < 1.7 is futile

FFP replaces a
of coagulation factors ... 30% coagulation factors ... fixed increase in factor ... @iEMPharmD #Pharmacology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... Environmental Risk Factors ... Epigentics Risk Factors ... Genetic Risk Factors ... relative with PBC Pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Acquired Risk Factors ... Thrombophilia: - Factor ... Venous #Arterial #pathophysiology ... #hematology #differential
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Pathogenesis and risk factors ... • Lifestyle Factors ... #Osteoporosis #pathophysiology
Apixaban Dose Adjustments in Atrial Fibrillation - ABCDs

Age > 80 years 
Body Weight <60kg 
Creatinine >=
DOUBLE of these Factors ... (2 or more factors ... Reduction #Eliquis #Pharmacology
Coagulation and kinin pathways

#Pharmacology #Pathophysiology #Coagulation #Kinin #Pathways #Cascade #Anticoagulants #Antithrombotics #Thrombolytics
kinin pathways #Pharmacology ... #Pathophysiology
Risk factors for atherosclerosis

Modifiable risk factors:
 - Dyslipidemia (elevated LDL, decreased HDL)
 - Tobacco smoking
 -
Risk factors for ... Modifiable risk factors ... Non-modifiable risk factors ... for females) #Pathophysiology