2503 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Phytonadione), 4-factor ... alfa (Andexxa), 4-factor ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
REBEL Review 90: Weight Based 4 Factor PCC Dosing 

#Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Weight Based 4 Factor ... PCC Dosing #Hematology ... #REBELReview #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Recombinant modified factor ... anticoagulant #hematology ... #management #pharmacology
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
Factor Activity ... Type of Factor ... ) Units of Factor ... #hemophilia #hematology ... #factorix
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor ... Coagulation #Cascade #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Patient has a factor ... Study #diagnosis #hematology ... pathophysiology #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
could be multiple factors ... pathways or a single factor ... Decreased factor ... Factor consumption ... #differential #hematology
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
Intrinsic = APTT Factors ... Extrinsic=PT Factors ... Common Pathway: Factors ... PET #diagnosis #hematology
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Factors V and VIII ... all coagulation factors ... least 80 units of factor ... von Willebrand factor ... Contents #Volume #Hematology
On the INR of FFP - why transfusing for INR < 1.7 is futile

FFP replaces a
of coagulation factors ... 30% coagulation factors ... fixed increase in factor ... @iEMPharmD #Pharmacology