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diagnosis differential bruising management petechiae rheumatology treatment anemia arterial blanching bruise cryofibrinogenemia cryoglobulinemia cryoglobulins dermatology dic disorders disseminated ecchymosis embolism
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... • Steroids • Vasculitis ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PT (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... intravascular coagulation ... discern these causes ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Infection - Vasculitis ... Complete blood count coagulation ... #Causes #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Acquired Risk Factors ... intravascular coagulation ... and other causes ... 19 - PNH - Vasculitis ... pathophysiology #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... 80-100 fL) • Bleeding ... #Anemia #MCV #Classification ... #Causes #Hematology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Purpura due to vasculitis ... ecchymosis) is caused ... are typical of coagulation ... factor deficiencies ... Measurement of coagulation
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... diagnosis #types #classification ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
insoluble globulin - Factor ... Paradoxical spontaneous bleeding ... malignancies, vasculitis ... cryoglobulins • Negative causes ... #hematology
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