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diagnosis hematology differential prolonged abnormal aptt bleeding bruising cascade models petechiae ptt anticoagulant anticoagulation apixaban arterial blanching bruise clot dabigatran
Coagulation Protein Tests (PT and PTT) #Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... Tests (PT and PTT ... ) #Coagulation ... #Tests #PTT #algorithm ... #differential #pathophysiology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Congenital intrinsic coagulation ... Pre-analytical cause ... intravascular coagulation ... aPTT #Prolonged #Causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... Causes include : ... Pre-analytical cause ... differential #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... Fibrinogen: ↓ • PT ... Treat primary cause ... #diagnosis #causes
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... • Prolonged PT ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... PT/NORMAL PTT: ... level NORMAL PT ... intravascular coagulation ... discern these causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Acquired Risk Factors ... Thrombophilia: - Factor ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... generated by Tissue Factor ... #Coagulation #Cascade ... thrombin #clot #PT ... models #hematology #pathophysiology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... Initiation phase caused ... , resulting in coagulation ... EricsMedicalLectures/ #Coagulation ... models #hematology #pathophysiology
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