165 results
Risk factors for atherosclerosis

Modifiable risk factors:
 - Dyslipidemia (elevated LDL, decreased HDL)
 - Tobacco smoking
 -
Risk factors for ... Modifiable risk factors ... Non-modifiable risk factors ... for females) #Pathophysiology ... Atherosclerosis #RiskFactors
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... Decreased factor ... aPTT #Prolonged #Causes ... #differential #hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Acquired Risk Factors ... • Nephrotic Syndrome ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Risk Factors Associated with Post-operative Pulmonary Complications 

Preoperative 
• Asthma/ COPD 
• Recent respiratory infection 
•
Risk Factors Associated ... pain control #RiskFactors ... anesthesia #surgery #causes
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Findings Risk factor ... Alzheimer's (99% of cases ... E4 allele Risk factors ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... (IBS) - Pathophysiology ... Algorithm Risk factors ... fatigue) Risk factors ... #Pathophysiology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Decreased factor ... aPTT #Prolonged #Causes ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology