55 results
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
factors. ... PF-3, platelet factor ... #Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Congenital • Factor ... Deficiency • Factor ... Diagnosis #Algorithm #Causes ... #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... aPTT #Prolonged #Causes ... #differential #hematology ... #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... aPTT #Prolonged #Causes ... #differential #hematology ... #coagulation
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Deficiency of Factor ... EricsMedicalLectures/ #Coagulation ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... commonly used anti-coagulation ... Direct thrombin (factor ... doac #comparison #table ... #management #drugs
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Factors V and VIII ... proteins, all coagulation ... factors, complement ... Contents #Volume #Hematology ... #Management #Table
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Review of the Coagulation ... Initiation phase caused ... , resulting in coagulation ... diagnosis #models #hematology ... #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Acquired Risk Factors ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential