39 results
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
von Willebrand factor ... Generation • Incr Factor ... Thrombosis #Bleeding #Clot ... #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Kidney stone type, corresponding urine sediment, urinary risk factors, and associated clinical settings.
#Diagnosis #Nephrology #Urine #Microscopy
, urinary risk factors ... Composition #Shapes #Table ... #RiskFactors
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Risk factors for atherosclerosis

Modifiable risk factors:
 - Dyslipidemia (elevated LDL, decreased HDL)
 - Tobacco smoking
 -
Risk factors for ... Modifiable risk factors ... Non-modifiable risk factors ... for females) #Pathophysiology ... Atherosclerosis #RiskFactors
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
the fibrin-rich clot ... Tranexamic #Acid #pathophysiology ... #hematology #TXA
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... Environmental Risk Factors ... Epigentics Risk Factors ... Genetic Risk Factors ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... protein C and S Pathophysiology ... significant fibrin clot ... treatment #management #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
of coagulation factors ... of thrombin and factor ... thrombin to form clots ... Scoring #diagnosis #hematology
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Factors V and VIII ... all coagulation factors ... von Willebrand factor ... Contents #Volume #Hematology ... #Management #Table