27 results
diagnosis symptoms msk management neurology causes pediatrics bone genetics hypercalcemia knee lesions orthopedics pagetsdisease peds pituitary psychiatry radiology secondary syndrome
Osteoarthritis (OA): Clinical findings • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
in subchondral bone ... contact between bony ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... involucrum • Paget ... lytic-blastic phase • Paget ... blade of grass sign ... #Differential #
Diagram of different types of bone tumors that can occur around the knee on XRay Age <
different types of bone ... involucrum • Paget ... lytic-blastic phase • Paget ... blade of grass sign ... #Differential #
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... easily/weakness, Bone ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... onto lateral hip Signs ... /Symptoms/Complications ... msk #diagnosis #pathophysiology ... #signs #symptoms
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Otitis Media: Complications ... becomes more severe Signs ... Otalgia (Ear Pain) fades ... #pathophysiology ... #symptoms #signs
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
tendon in the body ... pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Infertility • Decr Bone ... Syndrome #genetics #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology
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