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diagnosis treatment differential criticalcare gastroenterology infections infectiousdiseases pharmacology fungal idsa opportunistic algorithm cardiology comparison hivaids laboratory neurology prevention syndrome betadglucan
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
Pathogens, and Testing ... and pneumocystis False ... Glucan-containing gauzes ... other fungi • False ... #Sensitivity #Specificity
What is Fecal Occult Blood Testing (FOBT) • Screening for colorectal cancer in average risk population
Fecal Occult Blood Testing ... evaluation • False ... cauliflower, ETOH • False ... Does not change management ... to unnecessary testing
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
urinalysis, labs - Management ... renal biopsy - Management ... nephrotoxic drugs, treating ... ultrasonography - Manaqement ... percutaneous drainage, or stenting
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... and False Positives ... 96% • Higher specificity ... Galactomannan #Fungal #Testing
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Sensitivity & Specificity ... 96% - Higher specificity ... breakthrough IFI in HM • False ... recipients, CGD pts • False ... Frozen ice-pops (in setting
Urine Drug Screens - Common drugs that may cause false positive tests Amphetamines: Bupropion, Labetalol, Methylphenidate, Phenylephrine,
drugs that may cause ... false positive ... FalsePositive #Testing
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
age, which can cause ... a ↓ specificity ... (i.e. more false ... Specificity can ... adjusted d-dimer testing
Helicobacter Pylori (H. pylori) Infection - Diagnosis and Management - GrepMed Handbook Presentation: Dyspepsia / Peptic Ulcer
Diagnosis and Management ... Ag, Urea Breath Testing ... (UBT) - ↑ false ... hold 2w before testing ... past infection Management
"Imagine you're running airport security, screening passengers (tests) to catch dangerous items (diseases). Now meet your
Sensitivity and Specificity ... Specificity, on ... miss some real cases ... High specificity ... #medicine #specificity
USMLE Epidemiology and Biostatistics Summary Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Proves cause-effect ... Specificity (rule ... null when it’s false ... when it is indeed false ... but not on the causal
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