1779 results
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... histoplasmosis #Ferritin
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Algorithm Labs: Ferritin ... Structural: Celiac disease ... Diagnosis #Algorithm #ferritin
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... CRP, AST+ALT, ferritin ... AOSD: F>M, low ferritin ... AdultOnset #Stills #Disease
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Anemia of Chronic Disease ... - Ferritin-best ... Anemia #Chronic #Disease
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
anemia of chronic disease ... Anemia #Algorithm #Ferritin
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... • ↓Hgb • High ferritin ... the higher the ferritin ... the greater the disease ... onset #Stills #disease
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
MCHC, Serum Iron, Ferritin ... Anemia of Chronic Disease
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
deficiency if: • Ferritin ... Test for celiac disease
Hemochromatosis is a disorder associated with deposits of excess iron that causes multiple organ dysfunction. Hemochromatosis
and associated disease ... treatment of the diseases ... elevated serum ferritin ... Ferritin levels ... #Cirrhosis; #Ferritin
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
dysfunction, ↑ Ferritin ... • Autoimmune diseases ... Adult-onset Still disease