29 results
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology #
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... retroperitoneal fibrosis ... malignomas, and infectious ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... : • Mild disease ... Summary #diagnosis #rheumatology ... #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... diagnosis: 70 years old ... risk-stratification • Risks: infection ... only curative treatment ... #treatment #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
, Drug-induced Lupus ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... Fibrosis, Multiple ... ANA #patterns #rheumatology
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Interstitial Pneumonia - fibrosis ... leaking out of pulmonary ... intersitial space Infection ... Arthritis, Systemic Lupus ... Lung #Diseases #ILD
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
susceptibility, infectious ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SJIA], systemic lupus ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology