20 results
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology #
Hypereosinophilia (HE) Summary

 • Definition
 • When to Suspect?
 • A Partial Classification of Hypereosinophilia
 •
Hypereosinophilia (HE) Summary ... • A Partial Classification ... Presentations • Treatment ... Hypereosinophilia #HE #hematology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
- Summary Antinuclear ... severe disease Treatment ... : • Mild disease ... #diagnosis #rheumatology ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Summary • Epidemiology ... life-threatening • Treatment ... #Summary #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... diagnosis: 70 years old ... only curative treatment ... #treatment #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Diagnosis and Management ... Summary • Hypotension ... IV's, Consider IL ... Tamponade - Pulmonary ... #treatment #workup
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Rheumatoid Arthritis Summary ... exam and imaging Treatment ... Certolizumab, Golimumab), IL ... Arthritis #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology