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diagnosis management differential sle causes comparison erythematosus signs symptoms associations diseases interstitial lung vasculitis acidosis activation algorithm allergy ana antibodies
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... lupus. ... ConnectiveTissueDiseases #ILD ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Tissue Disease: • Systemic ... Polymyositis-dermatomyositis, Lupus ... • Idiopathic pulmonary ... fibrosis (IPF), ... #differential #pulmonary
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... nephritis, Class Ill ... Criteria #SLE #Systemic ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and progressive fibrosis ... calcinosis • Pulmonary ... : ILD (interstitial ... disease), PAH (pulmonary ... Scleroderma #SSc #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... : • Mild disease ... #Lupus #Erythematosus ... Summary #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... retroperitoneal fibrosis ... central nervous system ... lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... • Scleroderma (Systemic ... RNA Polymerase Ill ... #associations #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... , Drug-induced Lupus ... , Interstitial Pulmonary ... Fibrosis, Multiple ... ANA #patterns #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... Nephritis #Management #treatment ... #management #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
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