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diagnosis hematology algorithm causes classification hemolytic microcytic morphology rbc agglutinin anemias approach bloodcell calculation cold disease elevatedmcv index key macrocytic
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... bilirubin • ↑ Reticulocytes ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology Atlas ... syndrome, Increased reticulocyte ... spherocytosis, Hemolytic ... key #diagnosis #differential ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... of: Decreased Reticulocytes ... , MCV, MCH, MCHC ... Classification #Approach #Differential ... Algorithm #Causes #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (cell) volume (MCV ... acute blood loss, hemolysis ... for degree of anemia ... Diagnosis #Workup #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... -100): • Non-hemolytic ... , CKD • Hemolytic ... #Differential # ... Diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... ) - Differential ... Bleed • Hemolysis ... #Differential # ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
General Approach to Anemia ... - Differential ... hyper-proliferative 2) Exclude hemolysis ... haptoglobin) 3) Use MCV ... diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... • Bleeding • Hemolysis ... #MCV #Classification ... #Differential #
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... ) - Differential ... +/- increased reticulocytes ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
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