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diagnosis hematology differential causes hemolytic oncology chronic classification cll leukemia lymphocytic microscopy treatment workup abscess agglutinin allergy analysis antibiotics approach
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell disease ... #hematology #microscopy ... interpretation #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... • Peripheral blood ... smear + DAT + further ... malignancy, autoimmune disease
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss ... Normochromic RBCs on Smear ... Disease • Marrow ... Spherocytes on Smear ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... nose, ears, or fingers ... smear - RBC agglutination ... sensitize red blood ... #hemolytic #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Normal Blood Smear ... • Pancreatic Disease ... • Liver Disease ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... hematologic: Acute blood ... loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac disease
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... TSAT, sTfR • Blood ... extravascular) hemolysis ... Structural: Celiac disease ... #ferritin #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... result in severe anemia ... of Peripheral blood ... smear - Shows schistocytes ... anemia Indirect
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