9 results
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
the context of cutaneous ... Connective tissue disease ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... nemaline myopathy Cutaneous-centered ... Ig deposition disease ... #Differential #Diagnosis ... #hematology #oncology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... leukocytoclastic vasculitis ... #differential #diagnosis ... #dermatology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... nose, ears, or fingers ... presentation) • Cutaneous ... hemolytic #anemia #hematology ... #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... gangrenosum • Cutaneous ... Autoimmunity: • -MM/WM: Vasculitis ... Sneddon-Wilkinson disease ... #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... aphthous ulcers, cutaneous ... episcleritis as well as inner ... purpura: strong sign ... of cutaneous leukocytoclastic
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... ) • Cutaneous Lesions ... ) Differential Diagnosis ... : monoclonal TNF-aIpha ... #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... of cutaneous leukocytoclastic ... episcleritis as well as inner
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... Episcleritis Signs ... Leukocytoclastic vasculitis ... #dermatology #oncology