33 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Brushfield spots ... iris (pigmented spots ... incurved fifth finger ... #Downs #Syndrome
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral Syndrome ... findings • Anterior Knee ... Patellofemoral #Syndrome ... #pathophysiology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Hyperglycemic Hyperosmolar Syndrome ... infections, food binges ... #dka #hhs #pathophysiology
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
CREST Syndrome: ... hard nodules in fingers ... MTPs) #CREST #Syndrome ... #Pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
K-ATPase which imports ... - Refeeding Syndrome ... potassium #low #pathophysiology
Lemierre’s Syndrome - Pathophysiology

Lemierre’s is an infectious thrombophlebitis of the internal jugular vein.

 - It starts
Lemierre’s Syndrome ... - Pathophysiology ... - It starts ... #Lemierres #Syndrome ... #Pathophysiology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hypotension) DKA: Short ... respirations HHS: Longer
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... death Miller Fisher ... associated with Miller Fisher
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
lesions in the inner ... retinal nerve fiber ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... fractures • Short ... #PraderWilli #Syndrome ... #genetics #pathophysiology