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diagnosis algorithm hematology iron b12 cardiology cobalamin management msk pain pathophysiology pressure pulse rheumatology thrombocytosis vitamin acidosis arthritis celiac classification
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... (IBD, cancer) ... #differential # ... #nutrition
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Inflammation: IBD ... , Chronic disease ... #Causes #differential ... #nutrition
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... : SIBO, Celiac disease ... , IBD, Lymphoma, ... Stomach: Pernicious anemia ... #Cobalamin #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Inflammatory: • IBD ... disorders • Celiac disease ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Structural: Celiac disease ... Tropical sprue, IBD ... Bypass surgery, Bacterial ... #Anemia #Differential
Causes of Wide Pulse Pressure - Differential Diagnosis Physiologic: • Advanced age-arteriosclerosis (less compliant arteries) • Well
Causes of Wide Pulse ... less compliant arteries ... - Severe iron deficiency ... Chronic pulmonary diseases ... Arteriovenous fistula
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Myeloproliferative disease ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology #differential
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... and IBD Pearls: ... IDA and active IBD ... fatigue despite disease ... /other causes •
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
• Iron-deficiency ... anemia unresponsive ... without discernable cause ... microscopic colitis Differential ... Inflammatory (IBD
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
• Severe iron deficiency ... anemia (reduced ... Arteriovenous fistula ... coronary heart disease ... Worse outcomes in CKD
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