115 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Diagnosis Framework ... : Red/Dark urine ... : - RBC casts ... → Diagnostic of ... #Differential #Diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... proteinuria, RBC casts ... Nephrology if cause ... #Diagnosis #Algorithm
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... Algorithm #Nephrology #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
hematuria. ... RBC casts in urine ... but in severe cases ... Proteinuria #Nephrology #Diagnosis
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... - Differential Diagnosis ... - Structural - Cysts ... #Hematuria #Differential ... #Diagnosis #Causes
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... - Differential Diagnosis ... blood cells on urine ... RBCs and/or RBC casts ... #Differential #Diagnosis
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... Casts • Hyaline ... #Urine #Microscopy ... interpretation #diagnosis
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
microscopy • Red cell casts ... • White cell casts ... infection • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
• Urinary casts ... [(U Na x P Cr) / ... (P Na x U Cr)] ... #UNa #casts #glucosuria ... #hematuria
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Proteinuria - ++++ Hematuria ... Red blood cell casts ... Proteinuria - ++ Hematuria ... Red blood cell casts ... Table #Nephrology #Diagnosis