25 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... Proteinuria often ... but in severe cases ... Massive proteinuria ... #Nephrology #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Normal/low Proteinuria ... Red blood cell casts ... pressure - Raised Proteinuria ... Red blood cell casts ... edgarvlermamd - Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... (Positive urine ... albuminuria) - Active urine ... sediment - WBC/RBC casts ... #Nephrology #Differential
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
Nephrotic-range ... Urine total protein ... The presence of nephrotic ... is defined as nephrotic ... classification #CKD #nephrology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
develops new: • Proteinuria ... urine sediment ... dysmorphic RBCs, RBC casts ... , WBC casts) especially ... algorithm #sle #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... edgarvlermamd - Nephrology ... Microscopy #Diagnosis #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... sterile pyuria, WBC casts ... , mild tubular proteinuria ... , granular casts ... AIN #Algorithm #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... cell/white cell casts ... urine sediment ... #nephrotic #syndrome ... #nephrology