34 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Glomerular #Diseases ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... (Positive urine ... sediment - WBC/RBC casts ... Minimal change disease ... #Nephrology #Differential
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... also be seen if urine ... of glomerular disease ... contamination #Urine ... key #diagnosis #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... chronic kidney diseases ... #Urine #Microscopy ... #nephrology #interpretation
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
WBCs, or urine ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
proteins, documenting proteinuria ... as a disease state ... • Urinary casts ... [(U Na x P Cr) / ... #UNa #casts #glucosuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... cell/white cell casts ... impairment), heart disease ... because nephritic urine ... nephrotic #syndrome #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... Advanced kidney disease ... edgarvlermamd - Nephrology ... Microscopy #Diagnosis #Nephrology
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
progressive kidney disease ... Nephrotic-range proteinuria ... : - Urine total ... classification #CKD #nephrology ... #diagnosis #proteinuria