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diagnosis differential algorithm bypass gastric hepatorenal surgery anemia bilirubin bilirubinemia complications congenital cryofibrinogenemia deficiencies extravascular hemolysis hemolytic hrsaki hrsckd hrsnaki
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... nephrotoxics (e.g ... - No other cause ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • ... Diagnosis #Algorithm #Causes ... #Hematology
Complications after Bariatric Surgery Post Bariatric Intestinal Failure: • Severe protein malnutrition after bariatric surgery • More
Consider refeeding syndrome ... deficiencies) Dumping Syndrome ... Gastric bypass causes ... and Hepatology ... gastric #bypass #gastroenterology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... Post-Hepatic - Usually has ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery Nutrient Deficiencies: • Most frequent in the malabsorptive surgeries
• Persistent nausea ... testing and PTH q2 yrs ... and Hepatology ... Bypass #Surgery #bariatric ... #gastroenterology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... (HUS) • Other ... differential #diagnosis #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... (HRS) Definition ... Exclude other AKI causes ... liver insult (e.g ... #Syndrome #Hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
hyperbilirubinemia syndrome ... • Has a UGT1A1 ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... cryoglobulins • Negative causes ... Cryoglobulinemia • TTP, HUS ... Antiphospholipid syndrome ... #hematology
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