33 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... RBC casts in urine ... but in severe cases ... #Classification ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... osmolarity If cause ... of AKI remains ... • Interstitial nephritis ... #causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Cirrhosis • Nephrotic ... • Reduced GFR, AKI ... Hypo-osmolar urine
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Cirrhosis • Nephrotic ... • Reduced GFR, AKI ... Hypo-osmolar urine
General approach to AKI - Checklist

Urine electrolytes & FENa - Previously, it was believed that urine
General approach to AKI ... - Checklist Urine ... tubular interstitial nephritis ... @PulmCrit #AKI ... AcuteKidneyInjury #Nephrology
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... sodium retention, Urine ... • NSAlDs • AKI ... /CKD • Nephrotic ... Oncotic Pressure • Nephrotic
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... Urinary obstruction, Nephrotoxic ... PROBLEM ~80% of AKI ... IMPROVEMENT If the urine ... LorinskyMD #AKI
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Kidney Injury - Classification ... tubular necrosis (causes ... prolonged prerenal AKI ... Acute interstitial nephritis ... #diagnosis #nephrology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... sensitive) • AKI ... , AKD, rapidly progressive ... #Interstitial #Nephritis ... AIN #Algorithm #nephrology