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diagnosis pathophysiology algorithm differential neurology pediatrics spinalcord ankylosingspondylitis complications cushings disorders endocrinology genetics head hypercortisolism injury lesions management praderwilli syndromes
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... Syndromes Spinal ... Lower motor neuron symptoms ... Vertebral burst fracture ... #Cord #syndromes
Paget’s Disease: Pathogenesis and Clinical Findings • Incr serum CTx - marker of bone resorption •
Pathogenesis and Clinical ... , kyphosis and fractures ... formation #PagetsDisease ... pathophysiology #diagnosis #signs ... #symptoms
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
Pathogenesis and Clinical ... progresses) - X-ray ... -> Fracture of spine ... pathophysiology #diagnosis #signs ... #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Signs/Symptoms ... Incr Skeletal fractures ... , sleep apnea, cor ... pathophysiology #peds
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... and signs below ... compression by fractured ... MCTD, Sjogren syndrome
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
-> Pathologic fractures ... cord itself -> ... radiculopathy • Skull ... hearing loss #PagetsDisease ... #symptoms #complications
Algorithm for Management of Head Injuries in Children Primary survey: • Airway and cervical spine • Breathing
Airway and cervical spine ... of vomiting • Clinical ... of basal skull ... fracture, e.g. ... trama #pediatrics #peds
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Diagnosis and Clinical ... , pathological fractures ... /or MRI of the skull ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
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