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diagnosis hematology causes pregnancy aflp algorithm comparison hemolytic obgyn purpura table ttphus bruising cardiology dermatology disease disorders extravascular hemolysis hemorrhage
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Thrombocytopenia ... presents with coagulation ... pregnancy * Severe coagulation ... Bloodman #Pregnancy #Thrombocytopenia ... #AFLP #obstetrics
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Post-Partum Hemorrhage - Differential ... purpura (TTP) • HELLP ... intravascular coagulation ... (DIC) • Anti-coagulation ... Algorithm #Causes #Obstetrics
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Thrombocytopenia ... presents with coagulation ... defects. 1) HELLP ... Pregnancy #TTPHUS #HELLP ... #AFLP #Obstetrics
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP ... #Differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... intravascular coagulation ... (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... - Hemolytic anemia ... Vasculopathy #Purpura #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #Differential #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
, no necrosis HELLP ... features: Hemolysis, Thrombocytopenia ... Pregnancy #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
intravascular coagulation ... - Fanconi anaemia ... - Aplastic anaemia ... pediatrics #diagnosis #differential ... #thrombocytopenia
Hypertensive Disorders of Pregnancy Chronic Hypertension: • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg •
organ injury: thrombocytopenia ... preeclampsia patients • HELLP ... hypertension #htn #obstetrics ... #cardiology #differential
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